Organ transplantation becomes necessary when a person's organs have been damaged or destroyed by disease, an accident or a pre-existing condition linked to a birth defect. Some diseases may be more prominent in certain ethnic groups or specific to a gender. These conditions can result in end-stage failure of a vital organ, a life-threatening situation. Fortunately, scientific advances have made it possible for children and adults afflicted with these conditions to live longer, fuller lives through organ transplantation.

Diseases that Create the Need for Organ Transplants
The most common diseases or conditions necessitating organ  transplantation include: